Ultra-high throughput mapping of genetic design space
Kshitij Rai, Ronan W. O’Connell, Trenton C. Piepergerdes, Yiduo Wang, Lucas B. C. Brown, K Samra, Jack A. Wilson, Shujian Lin, Thomas H. Zhang, Eduardo M. Ramos, Andrew Sun, Bryce L. Kille, Kristen D. Curry, Jason W. Rocks, Todd J. Treangen, , Caleb J. Bashor
The paper introduces CLASSIC, a platform that maps sequence-to-function relationships in synthetic biology by combining long- and short-read sequencing to analyze gene circuits.
Nature · Jan 14, 2026Peer-reviewedSynthetic Biology