Kristen D. Curry

Shuttling, swapping and mixing: the rapid modular evolution of antiviral repertoires in temperate phages and their satellites

The paper identifies and characterizes defence hotspots in P2-like phages and P4-like satellites, revealing rapid modular evolution of antiviral systems through gene swapping and recombination.

Ultra-high throughput mapping of genetic design space

The paper introduces CLASSIC, a platform that maps sequence-to-function relationships in synthetic biology by combining long- and short-read sequencing to analyze gene circuits.

Logan: Planetary-Scale Genome Assembly Surveys Life's Diversity

Assembling the Sequence Read Archive (27.3 million accessions) with over 100-fold compression enables minutes-scale k-mer search and mining of enzymes, plasmids, proteins and viral reactivation.

Lightweight taxonomic profiling of long-read metagenomic datasets with Lemur and Magnet

This paper introduces Lemur and Magnet, lightweight tools for accurate taxonomic profiling of long-read metagenomic datasets, showing they run efficiently on laptops.

Reference-free Structural Variant Detection inMicrobiomes via Long-read Coassembly Graphs

This paper introduces rhea, a reference-free method for detecting structural variants in microbiomes using long-read coassembly graphs, showing improved performance over existing methods in simulated and real metagenomic data.

Fecal microbiota transplantation derived from Alzheimer's disease mice worsens brain trauma outcomes in wild-type controls

This study shows that fecal microbiota from Alzheimer's mice worsens brain injury outcomes in healthy mice.

Emu: Species-Level Microbial Community Profiling for Full-Length Nanopore 16S Reads

Emu provides species-level microbial community profiling using full-length 16S rRNA reads with improved accuracy over existing methods.