Single-cell RNA-seq identifies a reversible epithelial-mesenchymal transition in abnormally specified epithelia of p63 EEC syndrome
Eduardo Soares, Quan Xu, Qingqing Li, Jieqiong Qu, Yuxuan Zheng, Henriette H. M. Raeven, Karina O. Brandão, Isabelle Petit, Willem M.R. van den Akker, Simon J. van Heeringen, Daniel Aberdam, Fuchou Tang, Huiqing Zhou
The paper uses single-cell RNA-seq to identify a reversible epithelial-mesenchymal transition in p63 mutation-induced differentiation defects of human iPSCs.
Proceedings of the National Academy of Sciences · Aug 14, 2019Peer-reviewedDevelopmental Biology