Quan Xu

An integrated platform for high-throughput phenospace learning of 3D multilineage organoid systems

The paper introduces a platform for high-throughput spatial phenotyping of multilineage organoids, identifying pathway modulators and treatment strategies for PDAC.

Integrated cell atlas and tumoroids chart pancreatic cancer therapeutic targets

The paper integrates single-cell transcriptomes and spatial transcriptomics to identify therapeutic targets in pancreatic cancer by analyzing cell states and ligand-receptor interactions in tumoroids.

OncoPubMiner: A platform for oncology publication mining

OncoPubMiner is a platform that mines oncology publications to create structured knowledge bases, enabling efficient and accurate gathering of precision oncology insights from scientific articles.

ANANSE: An enhancer network-based computational approach for predicting key transcription factors in cell fate determination

ANANSE predicts key transcription factors in cell fate determination by analyzing enhancer-based regulatory networks across 18 human tissues.

Single-cell RNA-seq identifies a reversible epithelial-mesenchymal transition in abnormally specified epithelia of p63 EEC syndrome

The paper uses single-cell RNA-seq to identify a reversible epithelial-mesenchymal transition in p63 mutation-induced differentiation defects of human iPSCs.