Author

Willem M.R. van den Akker

Radboud University Medical CenterORCID 0000-0001-9492-4359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Huiqing ZhouiD· 2 shared Astrid R. Oudakker· 1 shared Britt MossinkiD· 1 shared Chantal SchoenmakeriD· 1 shared Daniel AberdamiD· 1 shared Dirk SchubertiD· 1 shared Eduardo Soares· 1 shared Fuchou TangiD· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Huiqing ZhouORCID

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedOct 30, 2019

Neuronal network dysfunction in a human model for Kleefstra syndrome mediated by enhanced NMDAR signaling

Monica Frega, Katrin Linda, Jason M. Keller…·Nael Nadif Kasri

This study shows that EHMT1 deficiency in human neurons leads to NMDAR hyperfunction, causing neuronal network dysfunction in Kleefstra syndrome, and demonstrates pharmacological rescue of these phenotypes.

137 citationstop 1%

humanbulk RNA-seq

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Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 14, 2019

Single-cell RNA-seq identifies a reversible epithelial-mesenchymal transition in abnormally specified epithelia of p63 EEC syndrome

Eduardo Soares, Quan Xu, Qingqing Li…·Huiqing Zhou

The paper uses single-cell RNA-seq to identify a reversible epithelial-mesenchymal transition in p63 mutation-induced differentiation defects of human iPSCs.

29 citations

humanscRNA-seq

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