Mild neonatal hypoxia disrupts adult hippocampal learning and memory and is associated with CK2-mediated dysregulation of synaptic calcium-activated potassium channel KCNN2
Art Riddle, Taasin Srivastava, Kang Wang, Eduardo Tellez, Hanna O’Neill, Xi Gong, Abigail O’Niel, Jaden A Bell, Jacob Raber, Matthew Lattal, James Maylie, Stephen A. Back
This study shows that mild neonatal hypoxia causes long-term hippocampal learning and memory deficits in mice through CK2-mediated dysregulation of KCNN2 channels, independent of white matter injury.
bioRxiv · Jul 10, 2024 · PreprintNeuroscience