Bioreactor cultures of brain endothelial cells produce extracellular vesicles with comparable characteristics as that of batch cultures
Balaji Govindaswamy, Chia-Chen Lu, Nikhila Achanta, Edward Y. Chen, Kristen Rebeles, Paromita Paul Pinky, Vivek Basudkar, Fauzia Parween, Devika Soundara Manickam
This study compares extracellular vesicles from bioreactor and batch cultures of brain endothelial cells, finding similar functional properties and protein content, with bioreactor cultures producing higher yields.
bioRxiv · Oct 6, 2026 · PreprintBioengineering