Vivek Basudkar

This study compares extracellular vesicles from bioreactor and batch cultures of brain endothelial cells, finding similar functional properties and protein content, with bioreactor cultures producing higher yields.

The paper compares sequential centrifugation and density gradient centrifugation for isolating mitochondria-containing large extracellular vesicles.

This study shows that mitochondria-containing large extracellular vesicles (lEVs) improve mitochondrial function in heat-stressed neurons and deliver mitochondria to motor neurons in vivo.