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Edwin H. Jacox

Centre National de la Recherche Scientifique

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Carine DiarraiD· 1 shared Christelle Dantec· 1 shared Christian CambillauiD· 1 shared Jacques Piette· 1 shared Kazuhiro R. NittaiD· 1 shared Marion Guéroult-Bellone· 1 shared Patrick LemaireiD· 1 shared Rémy Beulé Dauzat· 1 shared

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Recent·Most cited

Spacer sequences separating transcription factor binding motifs set enhancer quality and strength

Marion Guéroult-Bellone, Kazuhiro R. Nitta, Willi Kari, Edwin H. Jacox, Rémy Beulé Dauzat, Renaud Vincentelli, Carine Diarra, Ute Rothbächer, Christelle Dantec, Christian Cambillau, Jacques Piette, Patrick Lemaire

The paper shows that spacer sequences between transcription factor binding motifs influence enhancer activity and that randomizing these spacers can awaken dormant genomic clusters of TFBM.

bioRxiv · Jan 6, 2017 · PreprintDevelopmental Biology