Bioengineering Developmentally Inspired Matrix Vesicles as Designer Nanotherapeutics for Bone Regeneration
Flurina Staubli, Paula Sobrevals Alcaraz, Robert M. van Es, Harmjan R. Vos, Eelco Bergsma, Debby Gawlitta, Kenny Man
This paper bioengineers matrix vesicles from hypertrophic cartilage microtissues to enhance bone regeneration by improving their yield and therapeutic potential through BMP2 and hypertrophic conditioning.
Regenerative Biomaterials · Jan 1, 2026Peer-reviewedBioengineering