Effect of seizures on the severity of myelin vacuolization in a mouse model of megalencephalic leukoencephalopathy with subcortical cysts
Eelke Brouwers, Marjolein Breur, Maria Susana Jorge, Huibert D. Mansvelder, Marjo S. van der Knaap, Marianna Bugiani, Rogier Min
This study investigates whether seizures exacerbate myelin vacuolization and astrocyte swelling in a mouse model of MLC, finding no significant acute worsening of these features.
bioRxiv · Apr 23, 2024 · PreprintNeuroscience