Marianna Bugiani

This study uses human post-mortem brain slice cultures to investigate focal and subtle myelin damage in multiple sclerosis, showing the model's utility for studying human myelin pathology.

This study investigates whether seizures exacerbate myelin vacuolization and astrocyte swelling in a mouse model of MLC, finding no significant acute worsening of these features.

This study investigates how 4H leukodystrophy mutations affect cortical interneuron development using induced pluripotent stem cells and finds reduced GABAergic synapses and altered interneuron markers.

This study shows SARS-CoV-2 infection in macaques leads to brain inflammation and Lewy body formation, suggesting potential long-term neurological effects.

ISRIB ameliorates ISR deregulation and clinical signs in VWM mice.