Mechanism of Interaction Between the Transactivation Domain of N-MYC and the DNA-Binding Surface of TFIIIC5
Eoin N. Leen, Sharon Yeoh, Eka Sahak, E. A. Mitchell, Gemma C. Wildsmith, Matthew R. Batchelor, Antonio N. Calabrese, Gabriele Büchel, Richard W. Bayliss
The paper identifies the DNA binding domain of TFIIIC5 as a key interaction site for N-myc and elucidates the molecular mechanism of their interaction using structural and biophysical methods.
Nucleic Acids Research · Feb 23, 2026Peer-reviewedMolecular Biology