Multicellular model of temozolomide resistance in glioblastoma reveals phenotypic shifts in drug response and migratory potential
Victoria A. Kriuchkovskaia, Ela K. Eames, Sydney A. McKee, Paul J. Hergenrother, Rebecca Baab Riggins, Brendan A.C. Harley
This study uses a 3D hydrogel model to investigate TMZ resistance in GBM by examining drug response and migration in heterogeneous cell populations.
bioRxiv · Jul 8, 2025 · PreprintBioengineering