PfATP2 is an essential flippase on the Plasmodium falciparum surface that influences parasite sensitivity to antiplasmodial compounds
Deyun Qiu, Eleanor England, Adele M. Lehane
This study identifies PfATP2 as a surface flippase essential for Plasmodium falciparum growth and a target of antimalarial compounds, showing its role in phosphatidylserine internalization and drug sensitivity.
PLoS Pathogens · Oct 27, 2025Peer-reviewedMicrobiology