BioinformaticsbioRxivPreprint
MR-TRYX: A Mendelian randomization framework that exploits horizontal pleiotropy to infer novel causal pathways
Yoonsu Cho, Philip Haycock, Eleanor Sanderson…·Gibran Hemani
MR-TRYX identifies novel causal pathways by leveraging horizontal pleiotropy in Mendelian randomization analyses using GWAS summary data.