Bayesian inference of transcriptional branching identifies regulators of early germ cell development in humans
Christopher A. Penfold, Anastasiya Sybirna, John E. Reid, Aracely Castillo-Venzor, Elena Drousioti, Yun Huang, Murray Grant, Lorenz Wernisch, Zoubin Ghahramani A, M. Azim Surani
This paper develops a Bayesian pseudotime method to model transcriptional branching in human embryos and identifies regulators of PGC specification.
bioRxiv · Oct 15, 2018 · PreprintDevelopmental Biology