Molecular Characterization of the Progressive Landscape of Depression
Vandana Sharma, Elena Payna, Samuel González García, Lauren Fang, Kiran Boyinepally, Akiko Sumitomo, Toshifumi Tomoda, David A. Lewis, Robert Erne McCullumsmith, Etienne L. Sibille, Rammohan Shukla
This study identifies progressive molecular differences in depression across clinical stages using RNA-seq data, revealing shared and distinct pathways and cell-type-specific changes associated with symptom dimensions and therapeutic targets.
bioRxiv · May 23, 2026 · PreprintNeuroscience