The pathogenic mutant vimentin L387P disrupts endoplasmic reticulum organization and proteostasis
Elena Sala Lara, Dolores Pérez‐Sala, Alma E. Martínez
The paper shows that the vimentin L387P mutation disrupts ER organization and proteostasis by forming aggregates that sequester degradation components and impair ER function.
bioRxiv · Dec 8, 2025 · PreprintCell Biology