The glutamine-aspartate metabolic tradeoff between fast growth and metabolic flexibility.
Karin Ortmayr, Meret Ringwald, Laurentz Schuhknecht, Sébastien Dubuis, Eleni Paunossis, Martina Blaesi, Charly Jehanno, Sarah D. Grieder, Mohamed Bentires‐Alj, Moritz Mall, Mattia Zampieri
This study identifies a metabolic tradeoff between fast growth and flexibility in cancer cells and stem cells by analyzing glutamine and aspartate metabolism.
Genome biology · Oct 27, 2026Peer-reviewedCancer Biology