Karin Ortmayr

This study identifies a metabolic tradeoff between fast growth and flexibility in cancer cells and stem cells by analyzing glutamine and aspartate metabolism.

The paper maps TF-metabolite associations in cancer using a combined computational-experimental framework, revealing diverse TF dependencies in carbon metabolism.

This paper introduces a framework for large-scale dynamic metabolome drug profiling in mammalian cells, demonstrating its application to study dichloroacetate's toxic effects in ovarian cancer cell lines.