Author

Elia Mächler

UNSW Sydney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Jacob E. CorniD· 1 shared Jan C NelisiD· 1 shared Mandy Y. Boontanrart· 1 shared Simone PontaiD· 1 shared Viviana G Preiano· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Jacob E. CornORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Engineering of the Endogenous HBD promoter increases HbA2

Mandy Y. Boontanrart, Elia Mächler, Simone Ponta, Jan C Nelis, Viviana G Preiano, Jacob E. Corn

This study uses CRISPR-Cas9 to edit the endogenous {delta}-globin promoter to increase HbA2 expression in human erythroid cells, showing that multiple transcription factor elements are required for effective upregulation.

eLife · Jun 2, 2023Peer-reviewedGenetics