THC Reverses SIV-Induced Senescence in Astrocytes: Possible Compensatory Mechanism Against HIV Associated Brain Injury?
Alison R. Van Zandt, Miranda D. Horn, Tiffany A. Peterson, Sarah Y. Dickinson, Elise M. Frost, Andrew G. MacLean
This study shows THC protects astrocytes from HIV Tat-induced senescence and inflammation in rhesus macaques, but high-dose THC may harm glial survival.
Frontiers in Cellular Neuroscience · Sep 30, 2025Peer-reviewedNeuroscience