Author

Miranda D. Horn

Tulane UniversityORCID 0000-0001-9950-8418Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison R. Van ZandtiD· 2 shared Andrew G. MacLeaniD· 2 shared Ahmad A. SaiediD· 1 shared Cecily C. MidkiffiD· 1 shared Elise M. Frost· 1 shared Sarah Y. Dickinson· 1 shared Tiffany A. Peterson· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Alison R. Van ZandtORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 16, 2025

Neuroinvasion by Simian Immunodeficiency Virus Triggers Glial Senescence and Accelerated Neurodegeneration

Miranda D. Horn, Cecily C. Midkiff, Alison R. Van Zandt…·Andrew G. MacLean

This study shows that SIV infection in rhesus macaques leads to increased p16 and decreased SIRT1, associated with neurodegeneration and aging markers in multiple brain regions.

DOI 10.64898/2025.12.15.694426

ratspatial transcriptomics

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NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewedSep 30, 2025

THC Reverses SIV-Induced Senescence in Astrocytes: Possible Compensatory Mechanism Against HIV Associated Brain Injury?

Alison R. Van Zandt, Miranda D. Horn, Tiffany A. Peterson…·Andrew G. MacLean

This study shows THC protects astrocytes from HIV Tat-induced senescence and inflammation in rhesus macaques, but high-dose THC may harm glial survival.

4 citations

ratexperimental assay

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