Argonaute proteins regulate the timing of the spermatogenic transcriptional program
María de las Mercedes Carro, Alexis Dziubek, Amanda Touey-May, Elizabeth A. Popkowski, Mark Abdelmassih, Leah E Simon, Stephanie Tanis, Faraz Ahmed, Jennifer K. Grenier, Andrew Grimson, Paula E. Cohen
This study shows AGO3 and AGO4 regulate transcriptional silencing of XY-linked genes during meiosis in spermatogenesis, impacting fertility and sperm morphology.
bioRxiv · Dec 31, 2024 · PreprintDevelopmental Biology