GM-CSF modulates conserved ILC-like transcriptional states and myeloid cell signaling during ulceration in Crohns disease
Joshua K. Morrison, Ksenija Sabic, Neha Maskey, Sayali Talware, Nai-Yun Hsu, Colleen Chasteau, Elizabeth Aslinger, Jake T. Herb, Shikha Nayar, Rachel M. Levantovsky, Christopher Tastad, Rachel E. Moss, Alan Soto, Monica Garcia-Barros, Jessy Carol Ntunzwenimana, , Ling-shiang F. Chuang
This study shows GM-CSF reduces intestinal inflammation in Crohn's disease by modulating myeloid cell signaling and ILC-like transcriptional states.
bioRxiv · Oct 14, 2026 · PreprintImmunology