Cell BiologybioRxivPreprint
mTOR signaling regulates aberrant epithelial cell proliferative and migratory behaviors characteristic of airway mucous metaplasia in asthma
Katrina M. Kudrna, Elizabeth B. Staab, Evan M. Eilers…·John D. Dickinson
This study shows mTOR signaling drives aberrant epithelial behaviors in asthma, including proliferation and migration, and its inhibition reduces mucous metaplasia features.