Spatial programming of fibroblasts promotes resolution of tissue inflammation through immune cell exclusion
Patricia Reis Nisa, Christopher B. Mahony, Annie Hackland, Elizabeth Clay, Paulynn Suyin Chin, Lucy‐Jayne Marsh, Chrissy Bolton, Samuel Kemble, Charlotte G. Smith, Georgiana Neag, Ruchir Singh, Jason D. Turner, Andrew D. Filer, Karim Raza, Jean-Baptiste Richard, , Adam P. Croft
The paper uses multi-omic spatial analysis to identify fibroblast subsets in inflamed synovium that create tissue niches influencing immune cell trafficking and inflammation resolution.
bioRxiv · Sep 20, 2024 · PreprintImmunology