Molecular BiologyThe Journal of Cell BiologyPeer-reviewed
The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity
Adrienne E.D. Stormo, Farbod Shavarebi, Molly FitzGibbon…·Annie OF Hiniker
This study identifies TRIM1 as an E3 ligase that ubiquitinates LRRK2, regulating its localization, degradation, and toxicity in Parkinson's Disease.
20 citations