Histologic variants in bladder cancer harbor aggressive molecular features including TM4SF1 expression and a CA125+ cell state
Heiko Yang, Hanbing Song, Elizabeth Yip, Kevin Chang, Paul Allegakoen, Kevin L. Lu, Keliana Hui, Julia Pham, Corynn Kasap, Vipul Kumar, Janae Gayle, Bradley A. Stohr, Chien-Kuang Cornelia Ding, Arun P. Wiita, Maxwell V. Meng, , Franklin W. Huang
Single cell RNA sequencing of bladder cancer subtypes identified a CA125+ cell state linked to aggressive features and TM4SF1 as a therapeutic target.
bioRxiv · May 20, 2024 · PreprintCancer Biology