Author

Vipul Kumar

Boston Children's HospitalPrimary ORCID profile (0000-0001-7578-7467 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Vipul KumariD3 papers · Jaypee Institute of Information Technology

Biology Disciplines

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Cancer Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Arun P. WiitaiD· 2 shared Corynn KasapiD· 2 shared Franklin W. HuangiD· 2 shared Jonathan ChouiD· 2 shared Adam Yongxin YeiD· 1 shared Andrew LewisiD· 1 shared Bradley A. StohriD· 1 shared Chien-Kuang Cornelia DingiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Arun P. WiitaORCID

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3 papers

Recent·Most cited

Identification of TM4SF1 as a novel tumor-associated antigen in biliary tract cancers targetable by CAR-T cell therapy

Lorraine Nuniz, Julia H. Pham, Juliette Jacques, Corynn Kasap, Jocelin Chen, Jon Akutagawa, Josephine A. Hinneh, Chih-Hao Chang, Cindy Ament, Andrew Lewis, Arun P. Wiita, Jonathan Chou, R. Katie Kelley, Kwun Wah Wen, Vipul Kumar, Franklin W. Huang

This study identifies TM4SF1 as a tumor-associated antigen in biliary tract cancers and shows anti-TM4SF1 CAR-T cells inhibit tumor growth in vitro and in vivo.

bioRxiv · Oct 30, 2026 · PreprintCancer Biology

Histologic variants in bladder cancer harbor aggressive molecular features including TM4SF1 expression and a CA125+ cell state

Heiko Yang, Hanbing Song, Elizabeth Yip, Kevin Chang, Paul Allegakoen, Kevin L. Lu, Keliana Hui, Julia Pham, Corynn Kasap, Vipul Kumar, Janae Gayle, Bradley A. Stohr, Chien-Kuang Cornelia Ding, Arun P. Wiita, Maxwell V. Meng, , Franklin W. Huang

Single cell RNA sequencing of bladder cancer subtypes identified a CA125+ cell state linked to aggressive features and TM4SF1 as a therapeutic target.

bioRxiv · May 20, 2024 · PreprintCancer Biology

Ku70 suppresses alternative end-joining in G1-arrested progenitor B cells

Zhuoyi Liang, Vipul Kumar, Marie Le Bouteiller, Jeffrey Zurita, Josefin Kenrick, Sherry G. Lin, Jiangman Lou, Jianqiao Hu, Adam Yongxin Ye, Cristian Boboilă, Frederick W. Alt, Richard L. Frock

The paper shows that Ku70 suppresses alternative end-joining (A-EJ) in G1-arrested progenitor B cells, directing DSB repair toward classical nonhomologous end-joining (C-NHEJ) and preventing translocations.

Proceedings of the National Academy of Sciences · May 18, 2021Peer-reviewedGenetics