The emergence and loss of cyclic peptides in Nicotiana illuminate dynamics and mechanisms of plant metabolic evolution
Elliot M. Suh, Jakob Klaus Reinhardt, Jing‐Ke Weng
This paper resurrects an extinct burpitide cyclase from Nicotiana attenuata, revealing its evolutionary origin and function in producing novel cyclic peptides.
Proceedings of the National Academy of Sciences · Apr 14, 2025Peer-reviewedBiochemistry