Jakob Klaus Reinhardt

Discovery and isolation of novel capsaicinoids and their TRPV1-related activity

The paper identifies and isolates novel capsaicinoids from chilis, showing structural variations significantly impact TRPV1 activation and demonstrating non-pungent compounds modulate capsaicin's effects.

The emergence and loss of cyclic peptides in Nicotiana illuminate dynamics and mechanisms of plant metabolic evolution

This paper resurrects an extinct burpitide cyclase from Nicotiana attenuata, revealing its evolutionary origin and function in producing novel cyclic peptides.