Jing‐Ke Weng

The paper shows salicylic acid modulates SnRK1 and TOR to regulate NPR1 phosphorylation, linking immune responses with metabolic control in plants.

This paper introduces Boltz2ESI, a framework predicting enzyme-substrate interactions using a foundation model, outperforming existing methods by capturing active-site plasticity and evolutionary context.

This study identifies gene clusters involved in withanolide biosynthesis in ashwagandha using yeast metabolic engineering and characterizes key enzymes in the pathway.

This study traces the evolutionary origin of a plant halogenase by showing it evolved from a flavonol synthase gene through duplication, neofunctionalization, and structural changes.

The paper introduces a deep learning model, ICEBERG, for structural elucidation using tandem mass spectrometry, achieving high accuracy in identifying molecular structures from complex mixtures.

This paper introduces a genetically encoded fluorescent reporter for real-time measurement of polyamine levels in single cells and identifies a link between mitochondrial respiration and polyamine import in Parkinson's disease.

This paper resurrects an extinct burpitide cyclase from Nicotiana attenuata, revealing its evolutionary origin and function in producing novel cyclic peptides.

This paper reports the first complete life cycle and mitochondrial genome of the luminous ostracod Vargula tsujii, enabling future studies on bioluminescence biosynthesis and genomic manipulation.

The paper describes an engineered metabolic pathway in E. coli to produce nonnatural straight-chain amino acids via a recursive carbon-chain-extension cycle.

The paper generates genomes for three bioluminescent beetles to study the genetic basis of bioluminescence and finds at least two independent evolutionary origins of the trait.