Ribosomal protein RACK1 facilitates efficient translation of poliovirus and other viral IRESs
Ethan LaFontaine, Clare M. Miller, Natasha Permaul, Alex G. Johnson, Elliot T. Martin, Gabriele Fuchs
This study shows that RACK1 enhances poliovirus translation and infection by facilitating viral IRES-mediated translation, with reduced RACK1 leading to smaller viral plaques and delayed host translational shut-off.
Virology · Mar 25, 2020Peer-reviewedMolecular Biology