Quantifying Cell Traction Forces at the Individual Fiber Scale in 3D: A Novel Approach Based on Deformable Photopolymerized Fiber Arrays
Pierre Ucla, Joanne Lê-Chesnais, Henri Ver Hulst, Xingming Ju, Isabel Calvente, Elnaz Nematollahi, Ludovic Leconte, Jean Salamero, Isabelle Bonnet, Catherine Monnot, Hélène D. Moreau, Jessem Landoulsi, Vincent Semetey, Sylvie Coscoy
This paper introduces a method to measure cell traction forces at the individual fiber scale in 3D using deformable fiber arrays and finite element modeling, revealing how fiber properties influence cellular forces.
Proceedings of the National Academy of Sciences · Oct 13, 2025Peer-reviewedBiophysics