Author

Hélène D. Moreau

InsermORCID 0000-0001-5715-6864Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Eliane PiaggioiD· 2 shared Isabel Calvente· 2 shared Sylvie CoscoyiD· 2 shared Vincent SemeteyiD· 2 shared Zoé FusilieriD· 2 shared Alexandra Clément· 1 shared Amaury LerusteiD· 1 shared Ana‐Maria Lennon‐DuméniliD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Eliane PiaggioORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 29, 2025

Myeloid reprogramming by poly(I:C) recruits progenitor-exhausted CD8+ T cells and sensitizes rhabdoid tumors to PD-1 blockade

Valeria Sandoval Manríquez, Sofia Cavada-Silva, Kévin Beccaria…·Eliane Piaggio

This study shows that poly(I:C) reprograms myeloid cells in rhabdoid tumors, enhancing CD8+ T cell infiltration and improving response to PD-1 blockade.

DOI 10.64898/2025.12.29.696858

mousebulk RNA-seq

𝕏 PostBluesky

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedOct 13, 2025

Quantifying Cell Traction Forces at the Individual Fiber Scale in 3D: A Novel Approach Based on Deformable Photopolymerized Fiber Arrays

Pierre Ucla, Joanne Lê-Chesnais, Henri Ver Hulst…·Sylvie Coscoy

This paper introduces a method to measure cell traction forces at the individual fiber scale in 3D using deformable fiber arrays and finite element modeling, revealing how fiber properties influence cellular forces.

6 citations

imagingexperimental assay

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ImmunologybioRxivPreprintJan 17, 2025

Macrophages restrict tumor permissiveness to immune infiltration by controlling local collagen topography through a Tcf4-Collagen3 fibrotic axis

Zoé Fusilier, Franck Simon, Isabel Calvente…·Hélène D. Moreau

This study shows that macrophages control collagen network topography via Tcf4-Collagen3 pathway, influencing immune cell infiltration in tumors.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky