Sylvie Coscoy

This study identifies biomechanical changes in the tubular basement membrane as drivers of cyst formation in ADPKD, linking cilia and polycystin-1 function.

This paper introduces a method to measure cell traction forces at the individual fiber scale in 3D using deformable fiber arrays and finite element modeling, revealing how fiber properties influence cellular forces.

This study uses a kidney-on-chip model to decouple shear stress and pressure effects on tubule dilation in Pkd1-/- cells, revealing distinct mechanisms in different kidney cell types.

This study shows that macrophages control collagen network topography via Tcf4-Collagen3 pathway, influencing immune cell infiltration in tumors.