Allelic Variation at 9p21.3 Orchestrates Widespread RNA Splicing Shifts Governing Vascular Smooth Muscle Cell Plasticity
S. Suryavanshi, Huan Yang, Elsa Salido, Valentina Lo Sardo
This study shows that allelic variation at the 9p21.3 locus affects RNA splicing in vascular smooth muscle cells, leading to phenotypic changes linked to coronary artery disease.
bioRxiv · Feb 11, 2026 · PreprintGenetics