The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to an osteochondrogenic state
Elsa Salido, Carolina de Medeiros Vieira, José Verdezoto Mosquera, Rohan Zade, Parth Parikh, Shraddha Suryavanshi, Clint L. Miller, Valentina Lo Sardo
This study shows that the 9p21.3 CAD risk locus drives vascular smooth muscle cells to an osteochondrogenic state through ANRIL expression, leading to arterial calcification.
Arteriosclerosis Thrombosis and Vascular Biology · Mar 27, 2025Peer-reviewedCell Biology