Author

Emily Cao

Icahn School of Medicine at Mount Sinai

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Developmental Biology· 1

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Organism:Drosophila· 1 Approach:experimental assay· 1

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Cathie M. PflegeriD· 1 shared E. Premkumar ReddyiD· 1 shared Harnoor Singh· 1 shared Max LufiD· 1 shared Prashath KarunarajiD· 1 shared Stacey J. Baker· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperDevelopmental Biology

Cathie M. PflegerORCID

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1 paper

Recent·Most cited

A Drosophila model for Costello Syndrome caused by Ras mutation K117R

Prashath Karunaraj, Emily Cao, Harnoor Singh, Max Luf, Stacey J. Baker, E. Premkumar Reddy, Cathie M. Pfleger

This paper characterizes the Drosophila model of Costello Syndrome caused by the rare HRas K117R mutation, showing increased lethality, reduced body size, and specific phenotypes that suggest distinct roles for Raf-ERK and PI3K signaling pathways.

bioRxiv · Feb 3, 2025 · PreprintDevelopmental Biology