Drosophila models of PIGA-CDG mirror patient phenotypes
Holly J. Thorpe, Katie G Owings, Miriam C. Aziz, Madelyn Haller, Emily Coelho, Clement Y. Chow
This paper develops a Drosophila model of PIGA-CDG that recapitulates patient phenotypes, including seizures and movement disorders, and identifies cell-type-specific molecular changes.
bioRxiv · Oct 27, 2023 · PreprintGenetics