Disease-specific differences in particulate matter handling drive pathogenic responses in human derived nasal epithelial cells
Yiran Li, Bangqiao Yin, Emily Eberhardt, Xinyi Deng, Rachael Wasikowski, Hannah L. Briggs, Christina E Years, Jennifer P. Fox, John Chad Brenner, Lam C. Tsoi, Johann Eli Gudjonsson, Stuart Batterman, Mara C. Duncan, Marc B. Hershenson, Amarbir S. Gill
The paper investigates how particulate matter exposure affects nasal epithelial cells in chronic rhinosinusitis (CRS) and controls, finding amplified inflammatory and barrier dysfunction responses in CRS cells.
bioRxiv · May 29, 2026 · PreprintCell Biology