Cell-line specific role of Cathepsin B in triple-negative breast cancer growth, invasion and response to chemotherapy
Charlotte Kelley, Justinne R. Guarin, Emily Henrich, Jackson P. Fatherree, Claire M. Dunn, Anna Yui, Madeleine Julie Oudin
This study examines the cell-line specific role of CTSB in TNBC, finding that its knockout affects viability, invasion, and chemotherapy response differently in MDA-MB-231 and MDA-MB-468 cells.
bioRxiv · Nov 4, 2025 · PreprintCancer Biology