Author

Charlotte Kelley

Tufts UniversityORCID 0000-0001-5778-1432Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra B. Lantermann· 1 shared Alexandra Joseph· 1 shared Anna YuiiD· 1 shared Claire M. Dunn· 1 shared Emily Henrich· 1 shared Florence F. WagneriD· 1 shared Jackson P. FatherreeiD· 1 shared Jae Young Ahn· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Alexandra B. Lantermann

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 4, 2025

Cell-line specific role of Cathepsin B in triple-negative breast cancer growth, invasion and response to chemotherapy

Charlotte Kelley, Justinne R. Guarin, Emily Henrich…·Madeleine Julie Oudin

This study examines the cell-line specific role of CTSB in TNBC, finding that its knockout affects viability, invasion, and chemotherapy response differently in MDA-MB-231 and MDA-MB-468 cells.

1 citation

humanexperimental assay

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Cancer BiologybioRxivPreprintAug 13, 2025

p53Y220C-BET-bifunctionals (tPRIMEs) drive p53Y220C-mutant cancer cells into apoptosis

Charlotte Kelley, Jae Young Ahn, Scott F. Rusin…·Alexandra B. Lantermann

This study develops p53Y220C-tPRIMEs, bifunctional molecules that induce ternary complexes with p53Y220C and BET proteins, leading to apoptosis and growth inhibition in p53 mutant cancer cells.

3 citations

humanproteomics

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