Madeleine Julie Oudin

This study shows that chemotherapy activates fibroblasts in TNBC, promoting pro-invasive ECM production, and that nintedanib can suppress this effect.

This study examines the cell-line specific role of CTSB in TNBC, finding that its knockout affects viability, invasion, and chemotherapy response differently in MDA-MB-231 and MDA-MB-468 cells.

This study identifies splice-switching antisense oligonucleotides that correct splicing defects in SCN8A, reducing seizures and improving survival in a mouse model of genetic epilepsy.

This study shows TNBC cells activate sensory neurons via TRPV1, driving nerve outgrowth and tumor progression, with TRPV1 knockout reducing tumor growth and metastasis.

This study examines how alternative splicing and cellular context affect the functional properties of SCN8A variants associated with neurodevelopmental disorders.