Shape Factor Analysis as a Quantitative Framework for Assessing Spheroid and Organoid Morphology and Invasiveness
Brittany E. Schutrum, Jenny Deng, Ju Hee Kim, Amalie Gao, Emily Hur, Jack C. Crowley, Ling Lu, Matalin G. Pirtz, Coulter Q. Ralston, Alexander Yu. Nikitin, Claudia Fischbach
This paper develops a shape factor analysis method to quantify spheroid and organoid morphology, showing it provides more reliable morphology assessments than standard shape descriptors.
APL Bioengineering · Jul 1, 2026Peer-reviewedBioengineering