Ling Lu

This paper develops a shape factor analysis method to quantify spheroid and organoid morphology, showing it provides more reliable morphology assessments than standard shape descriptors.

The paper identifies a biomechanical pathway in beige adipocytes that mediates thermogenic activation through Myh9-FAK signaling, distinct from white adipocytes.

This paper introduces FPRM, a fast, label-free imaging method to monitor cellular metabolism using NAD(P)H autofluorescence, and demonstrates its application in tracking metabolic changes under various perturbations.