Carbohydrate-active enzymes from Akkermansia muciniphila breakdown mucin O-glycans to completion
Cassie R. Bakshani, Taiwo O. Ojuri, Bo Pilgaard, Jesper Holck, Ross S. McInnes, Radoslaw P. Kozak, Maria I. Zakhour, Sara Çakaj, Manon Kerouedan, Emily Newton, David N. Bolam, Lucy I. Crouch
This study characterizes carbohydrate-active enzymes from Akkermansia muciniphila to show they synergistically degrade mucin O-glycans to the core GalNAc.
Nature Microbiology · Jan 31, 2025Peer-reviewedBiochemistry