Lucy I. Crouch

This study identifies host-specific genomic and microbiome adaptations in Bifidobacterium across diverse animal hosts, revealing co-evolutionary dynamics and functional traits shaped by diet and phylogeny.

This study identifies PNGaseL from Flavobacterium akiainvivens as an enzyme with broad N-glycan specificity, outperforming PNGaseF and PNGaseA in cleaving diverse glycan structures.

This paper characterizes a PNGaseA enzyme from Bifidobacterium bifidum that preferentially strips N-glycans from peptides over proteins, revealing its structural basis for substrate specificity.

The paper shows that Escherichia coli and Bifidobacterium bifidum have a mutualistic interaction in degrading human milk oligosaccharides in healthy infants.

This study characterizes carbohydrate-active enzymes from Akkermansia muciniphila to show they synergistically degrade mucin O-glycans to the core GalNAc.